# Federal Register #FDA-2016-D-2343

FDA Draft Guidance Chapter on Chemical Hazards in Human Food

**Buyer:** Department of Health and Human Services / Food and Drug Administration
**Posted:** October 23, 2026
**Respond By:** January 22, 2027
**Identifier:** FDA-2016-D-2343

The U.S. Food and Drug Administration (FDA), within the Department of Health and Human Services, announced a draft guidance chapter on chemical hazards in human food.
- **Government agency:** FDA, Department of Health and Human Services.
- **Announcement:** Chapter 12, “Control of Chemical Hazards,” of FDA’s draft guidance on hazard analysis and risk-based preventive controls for human food.
- **Topics covered:** Radiological hazards; pesticide and drug residues; natural toxins; environmental contaminants, including toxic elements and PFAS; and contaminants arising during food processing.
- **Status and relevance:** The chapter describes FDA’s current thinking on complying with 21 CFR part 117. It is draft guidance, not a final requirement or procurement solicitation.
- **Procurement details:** No products, services, quantities, part numbers, OEMs, or vendors are requested.

### Description

The FDA announces the availability of an additional draft chapter of its multichapter industry guidance on hazard analysis and risk-based preventive controls for human food. The newly available chapter is Chapter 12: Control of Chemical Hazards, addressing known or reasonably foreseeable chemical hazards in food. The guidance is intended to explain FDA’s current thinking on complying with requirements under 21 CFR part 117, but is not final and is not currently in effect. Comments are due by January 21, 2027.

[View original listing](https://www.federalregister.gov/documents/2026/10/23/2026-21669/hazard-analysis-and-risk-based-preventive-controls-for-human-food-draft-guidance-for-industry)