# Simpler Grants.gov #PAR-28-093

NIH/NIDA grants for pilot studies preparing substance use and HIV research trials

**Buyer:** National Institutes of Health
**Posted:** October 19, 2026
**Respond By:** July 16, 2029
**Identifier:** PAR-28-093
**NAICS:** 541715

The National Institutes of Health is seeking research grant applications for pilot studies that prepare substance use and HIV research trials.
- **Government buyer:** National Institutes of Health (NIH), through the National Institute on Drug Abuse (NIDA).
- **Funding opportunity:** Grants for pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and services research trials.
- **Research areas:**
  - Prevention of substance use, misuse, or progression to substance use disorder.
  - Prevention, treatment, recovery, and services research, including research addressing co-occurring pain or medical and mental health conditions.
  - HIV eradication research in substance use settings or populations.
- **Award amount:** Maximum of $450,000 per award; minimum award, total program funding, and expected number of awards are not specified.
- **Eligibility and participation:** Eligible applicants include businesses, nonprofits, educational institutions, government entities, and tribal organizations. Foreign organizations and foreign components may participate, but foreign subawards and subcontracts are not eligible.
- **OEMs, vendors, and products:** No OEMs, vendors, specific products, part numbers, or quantities are identified.

### Description

This funding opportunity supports pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include developing interventions to prevent substance use or substance use disorder, prevention, treatment, or recovery services research, and HIV eradication research. The award maximum is $450,000; the source does not specify program funding, expected awards, or an award minimum. The response deadline is July 16, 2029.

[View original listing](https://simpler.grants.gov/opportunity/361204)
