# Simpler Grants.gov #PA-27-061

NIH Multidisciplinary Investigator-Initiated P01 Research Grants

**Buyer:** National Institutes of Health (NIH)
**Posted:** October 14, 2026
**Respond By:** May 25, 2029
**Identifier:** PA-27-061
**NAICS:** 541715, 541714, 541720, 541713

The National Institutes of Health is seeking multidisciplinary research proposals through its investigator-initiated Program Project grant opportunity.
- **Government buyer:** National Institutes of Health (NIH), through participating Institutes, Centers, and Offices (ICOs); the National Cancer Institute (NCI) is identified as the grantor contact.
- **Opportunity:** Investigator-initiated Program Project (P01) research grants.
- **Research program requirements:** Proposals should address a broad, multidisciplinary program organized around a specific scientific objective or theme and align with the mission and programmatic interests of one or more participating ICOs.
  - Each program project must include related research projects connected by a central scientific theme and an administrative core.
  - Shared resource cores are optional.
- **OEMs and vendors:** No commercial OEMs or vendors are identified; no products, part numbers, or quantities are requested.
- **Funding details:** No award amount or expected number of awards is specified. Cost sharing is not required.

### Description

The participating NIH Institutes, Centers, and Offices invite applications for investigator-initiated Program Project (P01) grants. A P01 supports a broadly based, multidisciplinary research program organized around a specific scientific objective or theme. Proposed projects must align with the programmatic interests and scientific missions of one or more participating ICOs. The program project includes related research projects with a shared scientific theme, an administrative core, and optional shared resource cores.

[View original listing](https://simpler.grants.gov/opportunity/361279)
