# Simpler Grants.gov #PAR-28-022

NCI P50 SPORE Grants for Translational Cancer Research

**Buyer:** National Institutes of Health
**Posted:** October 14, 2026
**Respond By:** September 25, 2029
**Identifier:** PAR-28-022
**NAICS:** 541714, 541715

The National Cancer Institute is seeking applications for P50 Specialized Programs of Research Excellence (SPORE) grants to advance translational cancer research.
- Buyer: National Institutes of Health (NIH), through the National Cancer Institute (NCI); the National Institute of Dental and Craniofacial Research (NIDCR) may jointly fund applications, depending on the research proposed.
- Purpose: Support investigator-initiated research to improve prevention, early detection, diagnosis, or treatment of an organ-specific cancer or a closely related group of cancers.
- Research requirement: Projects must use human biology approaches and reach a translational human endpoint during the grant project period.
- Funding and expected awards: The announcement lists $1,400,000 in program funding and anticipates 10 awards; this is program-level funding, not a stated value for each award.
- Eligibility: Qualifying government entities, nonprofits, educational institutions, and businesses may apply. Foreign entities and foreign components are not eligible.
- Products and services: No products or services are requested.

### Description

The National Cancer Institute invites applications for P50 Research Center Grants supporting Specialized Programs of Research Excellence (SPOREs), potentially jointly funded with the National Institute of Dental and Craniofacial Research. The program supports investigator-initiated translational research to improve prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a closely related group of cancers. Research must use human biology research approaches and reach a translational human endpoint within the grant project period. The opportunity lists program funding of $1,400,000 and expects 10 awards.

[View original listing](https://simpler.grants.gov/opportunity/360541)