# Federal Register #2026-21051

EPA establishes TSCA significant new use rules for certain chemical substances

**Buyer:** Environmental Protection Agency (EPA)
**Posted:** October 15, 2026
**Identifier:** 2026-21051

The Environmental Protection Agency (EPA) issued a regulatory action establishing significant new use rules under the Toxic Substances Control Act (TSCA).
- **Government agency:** Environmental Protection Agency (EPA); no specific sub-agency or office is identified.
- **Action:** Final significant new use rules (SNURs) apply to certain chemical substances covered by premanufacture notices and EPA Orders.
- **Requirement:** Anyone intending to manufacture, including import, or process a covered substance for a designated significant new use must notify EPA at least 90 days in advance and may not begin the activity until EPA has reviewed the notice, made a determination, and taken any required action.
- **Procurement relevance:** This is a regulatory action, not a procurement. No OEMs, vendors, products, services, quantities, or part numbers are identified.

### Description

The Environmental Protection Agency is issuing significant new use rules (SNURs) under the Toxic Substances Control Act for certain chemical substances that were the subject of premanufacture notices and are also subject to an EPA Order. Persons must notify EPA at least 90 days before manufacturing (including importing) or processing a covered substance for an activity designated as a significant new use. Such activity may not begin until EPA has reviewed the notification, made a determination, and taken any actions required by that determination.

[View original listing](https://www.federalregister.gov/documents/2026/10/15/2026-21051/significant-new-use-rules-on-certain-chemical-substances-26-1)