Award
National Institute on Drug Abuse 5R01DA050180-05
PACAP-Dependent Coordination of Glutamate Signaling between Neurons and Astrocytes
Recipient
Marquette University
Award Amount
$411,246.00
Ceiling
$411,246.00
Awarded
May 02, 2025
Identifier
5R01DA050180-05
The project investigates how neurons regulate glutamate release from astrocytes via PACAP in the nucleus accumbens and its role in cocaine addiction behaviors, aiming to understand molecular mechanisms and behavioral outcomes.
Description
This project focuses on the role of PACAP in glutamate signaling related to cocaine addiction, with multiple aims exploring molecular mechanisms, pathway-specific regulation, and behavioral outcomes.