Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK126786-05
DISSECTING THE LINK BETWEEN UREAGENESIS AND HEPATIC GLYCOGEN METABOLISM
Recipient
Baylor College of Medicine, Houston, TX, United States
Award Amount
$463,829.00
Ceiling
$463,829.00
Awarded
January 20, 2025
Identifier
5R01DK126786-05
Research project studying the link between urea cycle dysfunction and hepatic glycogen metabolism to understand liver disease in urea cycle disorders and develop potential treatments.
Description
This project aims to investigate the biochemical mechanisms underlying hepatic glycogen accumulation in urea cycle disorders and test potential interventions to prevent liver disease in these conditions. The research involves biochemical, genetic, and isotope studies in mouse models, with potential implications for human disease management.