Award

NIH Reporter #1K08HD120866-01

The Role of Gut Microbiota-Derived Butyrate in Inflammation and Neurological Outcomes after Neonatal Hypoxic-Ischemic Encephalopathy

Recipient

University of Texas Health Science Center Houston

Award Amount

$162,000.00

Ceiling

$162,000.00

Awarded

March 27, 2026

Identifier

1K08HD120866-01

This award supports research on the role of gut microbiota-derived butyrate in modulating inflammation and improving neurological outcomes after neonatal hypoxic-ischemic encephalopathy, focusing on immune response and brain development.

Description

Research project to define how gut microbiota-derived butyrate modulates inflammation, enhances regulatory T cell maturation, and promotes anti-inflammatory microglial polarization to improve long-term outcomes after neonatal hypoxic-ischemic encephalopathy (nHIE).

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