Award
NIH Reporter #1K01AA033159-01
Investigating Oleoylethanolamide (OEA) as a Novel Multi-System Based Therapeutic for Young Adults with Alcohol Use Disorder
Recipient
Medical University of South Carolina, Charleston, SC, United States
Award Amount
$195,912.00
Ceiling
$195,912.00
Awarded
July 24, 2026
Identifier
1K01AA033159-01
A clinical trial funded by the National Institute on Alcohol Abuse and Alcoholism to study the effects of OEA on inflammation, microbiome, neurocognitive function, and alcohol use in young adults with AUD, aiming to develop innovative multisystem-informed interventions.
Description
This pilot clinical trial will evaluate the potential of oleoylethanolamide (OEA), a naturally occurring endocannabinoid-like lipid, to modulate brain, immune, and microbiome systems and reduce alcohol use behaviors in young adults with Alcohol Use Disorder (AUD). The project aims to provide foundational data to inform larger trials and support the development of targeted, multi-system interventions for AUD in this high-risk population.