Award

NIH Reporter #11294335

Hyperglycemia and Adverse Pregnancy Outcome Study-Cardiovascular Health of HAPO Offspring (HAPO CVH)

Recipient

Lurie Children’s Hospital of Chicago

Award Amount

$1,762,069.00

Ceiling

$1,762,069.00

Awarded

June 01, 2026

Identifier

11294335

Award for a study investigating the impact of in utero cardiometabolic environment on cardiovascular health in offspring, funded by NHLBI, involving multiple health assessments and collaboration with Lurie Children’s Hospital of Chicago.

Description

The project involves a comprehensive investigation of the cardiometabolic in utero environment and its association with cardiovascular health and arterial injury in young-adult offspring. It aims to understand the timing, pathways, and mechanisms of intergenerational transfer of cardiovascular disease risk. The project includes assessments of blood pressure, adiposity, lipids, glycemia, lifestyle behaviors, carotid ultrasonography, and DNA methylation analysis. It is part of the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study cohort and involves collaboration with the Lurie Children’s Hospital of Chicago. The project is funded by the National Heart Lung and Blood Institute (NHLBI).

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