Award
NIH Reporter #1ZIAES100475-24
Discovery And Functional Genomics Of Environmental Response Genes
Recipient
NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES, UNITED STATES
Award Amount
$127,049.00
Ceiling
$127,049.00
Awarded
April 27, 2024
Identifier
1ZIAES100475-24
This award supports research on epigenomic profiling of blood cell types to identify smoking-related DNA methylation changes and their links to disease risk, with a focus on bronchopulmonary dysplasia in preterm infants.
Description
Epigenomic profiling of isolated blood cell types reveals highly specific B cell smoking signatures and links to disease risk. The project involves epigenome-wide association studies (EWAS) and transcriptome analysis focusing on biomarkers for early detection and prevention of bronchopulmonary dysplasia (BPD) in preterm infants, including analysis of cord blood DNA methylation and RNA expression.