Award
National Institute of General Medical Sciences 5R01GM131004-08
Defining the role of lipid metabolism in nuclear envelope identity and dynamics
Recipient
Yale University, New Haven, CT, United States
Award Amount
$346,515.00
Ceiling
$346,515.00
Awarded
April 27, 2026
Identifier
5R01GM131004-08
A research project funded by the National Institute of General Medical Sciences to study lipid metabolism's role in nuclear envelope formation and function, with potential implications for various diseases.
Description
This project aims to elucidate the mechanisms regulating nuclear envelope formation and maintenance, with implications for understanding diseases such as cancer, muscular dystrophy, and progeria. The research focuses on how lipid metabolism controls nuclear envelope formation and function, using vertebrate tissue culture cells to study protein targeting, lipid metabolism, and membrane sensing related to the nuclear envelope.