Award
National Institute of Neurological Disorders and Stroke 5R01NS126499-03
Generation and analysis of mouse models to define the roles of the ALS-associated factor Zfp106/ZNF106 in neurodegeneration
Recipient
University of California, San Francisco
Award Amount
$420,917.00
Ceiling
$420,917.00
Awarded
December 30, 2025
Identifier
5R01NS126499-03
The award funds research at the University of California, San Francisco to study the role of the ZNF106 gene in ALS neurodegeneration through mouse models and genetic analysis, aiming to understand the disease mechanisms and potential protective roles of ZNF106.
Description
This project investigates the genetic functions of ZNF106 in ALS neurodegeneration using mouse models, cell culture assays, and genetic analysis to understand how mutations in ZNF106 contribute to ALS.