Award
National Heart, Lung, and Blood Institute 5R01HL151228-04
Genetic and hypoxic control of a lncRNA axis orchestrates endothelial reprogramming in pulmonary hypertension
Recipient
University of Pittsburgh at Pittsburgh, PA, United States
Award Amount
$677,648.00
Ceiling
$677,648.00
Awarded
June 12, 2026
Identifier
5R01HL151228-04
The project aims to define the role of the lncRNA-KMT2E axis in pulmonary hypertension, focusing on genetic and epigenetic factors to develop new therapies.
Description
This NIH grant project investigates the role of the lncRNA KMT2E-AS1 in pulmonary hypertension (PH), exploring genetic variants, epigenetic mechanisms, and molecular pathways involved in PH to develop targeted therapies.