Award
National Institute of Allergy and Infectious Diseases 1K08AI194971-01
Expanded evaluation of the role of antibody-dependent innate effector function in TB disease progression in HIV co-infected individuals
Recipient
Brigham and Women's Hospital, Boston, MA, United States
Award Amount
$194,400.00
Ceiling
$194,400.00
Awarded
September 11, 2025
Identifier
1K08AI194971-01
This award supports research investigating how HIV affects antibody-dependent innate immune functions related to tuberculosis progression in co-infected individuals, aiming to develop improved diagnostics and treatments.
Description
Research to dissect the impact of HIV on antibody-dependent innate effector functions and identify key functional correlates of TB disease progression and control in HIV-coinfected individuals, providing mechanistic insights into antibody-mediated immunomodulation to inform diagnostics, therapeutics, and vaccines.