Award
National Institute on Minority Health and Health Disparities 5U54MD007602-39
A multiomic analysis of HER2/ERBB2 in African American men with prostate cancer
Recipient
Morehouse School of Medicine, Atlanta, GA, United States
Award Amount
$314,706.00
Ceiling
$314,706.00
Awarded
July 28, 2026
Identifier
5U54MD007602-39
A research award to study HER2/ERBB2 overexpression in African American men with prostate cancer to understand its impact on disease progression, treatment resistance, and survival disparities, using multiomic analyses.
Description
This research project investigates the role of HER2/ERBB2 overexpression in prostate cancer progression and treatment resistance among African American men, aiming to understand molecular mechanisms driving disparities in outcomes. The study includes confirming HER2 correlation with West African ancestry, identifying genetic variations linked to HER2 amplification, and determining multiomic signatures predictive of treatment resistance and survival.