Award
National Institute of Mental Health 7R01MH129558-04
A Confirmatory Efficacy Trial of Engaging a Novel Sleep/Circadian Rhythm Target as Treatment for Depression in Adolescents
Recipient
CHILDREN'S HOSPITAL OF LOS ANGELES
Award Amount
$778,871.00
Ceiling
$778,871.00
Awarded
April 10, 2026
Identifier
7R01MH129558-04
NIH awarded a grant to Children's Hospital of Los Angeles for a clinical trial testing a novel sleep/circadian rhythm treatment for adolescent depression, with a $778,871 budget.
Description
This is a NIH grant project for a clinical trial on depression treatment in adolescents, focusing on sleep and circadian rhythm interventions. The project involves a randomized controlled trial with a sample size of 200 adolescents, aiming to confirm the efficacy of a sleep intervention (TranS-C) in improving depression outcomes by lengthening the phase angle difference between melatonin onset and waketime.