Award
National Eye Institute 1R21EY037026-01A1
Elucidating competence and fate choice dynamics during retinal development
Recipient
University of Colorado Denver, Aurora, CO
Award Amount
$415,012.00
Ceiling
$415,012.00
Awarded
August 15, 2025
Identifier
1R21EY037026-01A1
Research project funded by the National Eye Institute to study gene regulatory and signaling mechanisms in retinal development to support regenerative therapies for vision loss.
Description
This project aims to understand the gene regulatory and signaling mechanisms that control cellular competence and fate choices during retinal development, with the goal of developing regenerative therapies. It focuses on how retinal progenitor cells decide between different cell fates during development, particularly the role of Notch signaling, to inform regenerative strategies.