Award
NIH Reporter #5R01CA269740-04
Targeting the Microenvironment/Oncogene Cooperation to treat poor prognosis T-ALL
Recipient
Beckman Research Institute/City of Hope
Award Amount
$519,672.00
Ceiling
$519,672.00
Awarded
February 18, 2026
Identifier
5R01CA269740-04
Research grant to study the interaction of oncogenic signaling and microenvironment in T-ALL to develop new therapeutic strategies for relapsed and refractory cases.
Description
This project aims to define how cooperation between oncogenic signaling and the microenvironment affects therapy of poor prognosis T-ALL. It will build a foundation for validating new molecular targets in relapsed and refractory T-ALL and provide a proof-of-principle for an alternative strategy considering entire molecular circuits during therapy development.