Award
National Institute of Allergy and Infectious Diseases 5R01AI166049-05
Genomic consequences of schistosome hybridization
Recipient
Texas Biomedical Research Institute, San Antonio, TX, United States
Award Amount
$613,689.00
Ceiling
$613,689.00
Awarded
September 09, 2025
Identifier
5R01AI166049-05
NIH funded research project to study genomic consequences of schistosome hybridization using genome sequencing and experimental crosses in rodents to understand hybridization frequency, effects, and geographic distribution.
Description
This project aims to study hybridization between schistosome species infecting humans (S. haematobium) and livestock (S. bovis). Using genome sequencing of field-collected schistosomes, the research will determine the frequency and consequences of hybridization in natural populations. The study will include experimental crosses to assess how hybridization impacts parasite traits and will examine the role of rodent hosts in hybridization.