Award
National Eye Institute 5R01EY029823-05
Novel hybrid molecule with both IOP lowering and neuroprotective effects for treatment of glaucoma
Recipient
University of North Texas Health Science Center, Fort Worth, TX
Award Amount
$370,000.00
Ceiling
$370,000.00
Awarded
August 15, 2024
Identifier
5R01EY029823-05
The award supports research to develop a hybrid nitric oxide donating and superoxide dismutase mimetic compound encapsulated in nanoparticles to lower intraocular pressure and protect retinal ganglion cells in glaucoma, aiming to optimize dosing and evaluate efficacy for potential human trials.
Description
This project focuses on developing a novel therapeutic approach for glaucoma involving hybrid molecules that lower intraocular pressure and provide neuroprotection, utilizing nanoparticle delivery systems.