Award
NIH Reporter #1R35GM165612-01
Molecular determinants of lipid-protein recognition
Recipient
Neville Bethel
Award Amount
$384,394.00
Ceiling
$384,394.00
Awarded
July 13, 2026
Identifier
1R35GM165612-01
Award for research on lipid-protein interactions using advanced computational and experimental methods to develop predictive models and biosensors, aiding disease understanding.
Description
This project aims to investigate the biophysical interactions of lipid headgroups with proteins, utilizing deep learning, molecular dynamics, and de novo protein design. The goal is to develop models predicting lipid-protein interactions and create biosensors for lipids such as GM2, contributing to understanding diseases like Niemann-Pick Disease Type C.