Award
National Institute of Allergy and Infectious Diseases 5R01AI056189-22
B. thuringiensis crystal proteins as powerful next-generation anthelmintics
Recipient
University of Massachusetts Medical School
Award Amount
$740,147.00
Ceiling
$740,147.00
Awarded
June 10, 2026
Identifier
5R01AI056189-22
NIH awarded a grant to research Bacillus thuringiensis crystal proteins as next-generation anthelmintics, focusing on developing effective and safe treatments for gastrointestinal nematodes.
Description
This NIH grant supports research on Bacillus thuringiensis (Bt) crystal (Cry) protein anthelmintics, aiming to develop effective formulations and hybrid proteins to target gastrointestinal nematodes. The project includes in vitro and in vivo studies, with a focus on safety and efficacy to meet WHO guidelines for new anthelmintic drugs.