Award
National Institute of Environmental Health Sciences 5F31ES036890-03
The role for cell cycle regulators in trichloroethylene induced Parkinson's dementia
Recipient
University of Alabama at Birmingham
Award Amount
$41,404.00
Ceiling
$41,404.00
Awarded
July 15, 2026
Identifier
5F31ES036890-03
Research grant awarded to study how trichloroethylene exposure affects cell cycle regulators in Parkinson's disease dementia, aiming to find therapeutic targets.
Description
The project investigates the role of environmental toxicants, specifically trichloroethylene (TCE), in influencing cognitive impairments associated with Parkinson’s disease dementia. It focuses on aberrant CDK5 activation and increased cellular senescence in neural stem cells, aiming to identify therapeutic targets to slow disease progression.