Award
National Institute of General Medical Sciences 1R01GM164613-01
Computational modeling and measurement of mitotic spindle length control, stability and elongation
Recipient
University of Colorado
Award Amount
$426,262.00
Ceiling
$426,262.00
Awarded
June 01, 2026
Identifier
1R01GM164613-01
NIH awarded a grant to University of Colorado for research on mitotic spindle length control and stability, focusing on the role of nuclear envelope forces in closed mitosis, with a project duration from 2026 to 2030 and funding of $426,262.
Description
This NIH grant project aims to determine the interplay between force and biochemistry responsible for regulated spindle length, stability, and elongation in closed mitosis. It will identify new principles of spindle regulation using a genetically tractable system, develop computational models, create new mutants and protocols, and integrate advanced assays to study spindle dynamics.