Award
National Institute on Drug Abuse 5DP1DA058349-04
Developing a computational platform for induced-fit and chemogenetic drug design
Recipient
Vanderbilt University
Award Amount
$475,500.00
Ceiling
$475,500.00
Awarded
March 20, 2026
Identifier
5DP1DA058349-04
Award to Vanderbilt University for developing a computational drug design platform targeting the μ-opioid receptor, funded by NIDA with $475,500 for FY 2026.
Description
The project aims to develop a computer-aided drug discovery platform leveraging deep learning and structural modeling to identify biased agonists and DREADDs for the μ-opioid receptor. The award is from the National Institute on Drug Abuse (NIDA), with a total budget of $475,500 for fiscal year 2026. The project duration is from May 1, 2023, to March 31, 2028. The primary investigator is Benjamin Patrick Brown, an Assistant Professor (Tenure-Track) at Vanderbilt University. The project involves collaboration with multiple researchers and aims to establish an iterative computational-experimental feedback loop.