Award
Eunice Kennedy Shriver National Institute of Child Health and Human Development 5R01HD112076-02
Dose based aspirin pharmacokinetics and pharmacodynamics in pregnancy and association with pregnancy outcomes
Recipient
Thomas Jefferson University, Philadelphia, PA, United States
Award Amount
$663,370.00
Ceiling
$663,370.00
Awarded
December 30, 2025
Identifier
5R01HD112076-02
This NIH-funded research project investigates aspirin pharmacokinetics and pharmacodynamics in pregnancy to optimize dosing and improve pregnancy outcomes in high-risk patients.
Description
A randomized controlled trial of 300 high-risk singleton pregnancies to determine optimal aspirin dosing during pregnancy to improve maternal and child health outcomes. The study will assess aspirin response and its association with perinatal outcomes, aiming to develop a novel clinical care paradigm.