Award
NIH Reporter #5UM1HG012649-05
Molecular and cellular characterization of essential human genes.
Recipient
Northwestern University, Chicago, IL, United States
Award Amount
$1,612,686.00
Ceiling
$1,612,686.00
Awarded
August 11, 2026
Identifier
5UM1HG012649-05
Award for research on essential human genes using inducible protein depletion in stem cells, funded by NIH and managed by NHGRI, totaling approximately $1.61 million.
Description
The project involves creating a barcoded, chemically inducible, and reversible system to deplete proteins of interest in human induced pluripotent stem cells. The project aims to generate null alleles for 250 critical genes, focusing on essential genes implicated in human diseases. The project is funded by NIH (RFA-HG-21-029) and managed by the National Human Genome Research Institute. The project duration is from September 22, 2022, to June 30, 2027.