# NIH Reporter #5R01EY034565-04

Optimizing methotrexate use for the management of chronic pediatric non-infectious uveitis

**Recipient:** Cincinnati Childrens Hosp Med Ctr

**Award Amount:** $560,861.00
**Ceiling:** $560,861.00

**Awarded:** April 06, 2026

**Identifier:** 5R01EY034565-04

The National Eye Institute funded a study of methotrexate response in pediatric non-infectious uveitis. Researchers will follow children starting methotrexate and evaluate clinical, imaging, and gene-expression predictors to help guide treatment decisions.

### Description

NIH research project investigating clinical, imaging, and biologic factors that predict methotrexate response in children with chronic non-infectious uveitis, with the aim of improving treatment selection and reducing ocular damage.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11308671)