Award
Illinois Department of Veterans Affairs 5I01BX000152-15
Regulation of Intestinal Bile Acid Absorption in Health and Cholesterol-Related Disorders
Recipient
JESSE BROWN VA MEDICAL CENTER
Awarded
October 06, 2025
Identifier
5I01BX000152-15
Research project awarded to investigate bile acid absorption regulation and its impact on cholesterol-related disorders, aiming to develop treatments for hypercholesterolemia and metabolic diseases.
Description
The project focuses on investigating mechanisms to decrease bile acid absorption and impact fatty acid and cholesterol metabolism, relevant to hypercholesterolemia and cardiovascular risk. The study involves in vitro models, transgenic mice, and dietary interventions. The research is highly significant for developing treatments for hypercholesterolemia and related metabolic disorders.