Award
National Cancer Institute 5R01CA275762-04
Novel Biomarkers Predicting Blood Clots in Ovarian Cancer
Recipient
University of Texas MD Anderson Cancer Center
Award Amount
$441,654.00
Ceiling
$441,654.00
Awarded
July 14, 2026
Identifier
5R01CA275762-04
This NIH-funded project at the University of Texas MD Anderson Cancer Center focuses on identifying novel biomarkers predicting blood clots in ovarian cancer patients. It investigates the role of mitochondria and podoplanin in venous thromboembolism risk, aiming to improve risk prediction and develop targeted therapies.
Description
The project aims to identify biomarkers for blood clots in ovarian cancer by investigating tumor specimens, blood samples, and clinical data to determine risk factors for venous thromboembolism (VTE) in ovarian cancer patients. The research explores the role of cancer cell-derived mitochondria and podoplanin in VTE risk, including murine models and genetic analysis to identify predictive biomarkers and potential therapeutic targets.