Award
National Cancer Institute 5F31CA306147-02
Dysregulated DNA replication forks as targets for formaldehyde mutagenesis
Recipient
Medical University of South Carolina, Charleston, SC
Award Amount
$48,215.00
Ceiling
$48,215.00
Awarded
July 29, 2026
Identifier
5F31CA306147-02
This award funds a research project at the Medical University of South Carolina to study how dysregulated DNA replication forks contribute to formaldehyde-induced mutagenesis, with goals to identify mutational signatures and individuals at risk for formaldehyde-related cancer.
Description
Research project investigating replication forks as cellular sources of single-stranded DNA targeted by formaldehyde, aiming to understand formaldehyde-induced mutagenesis and identify biomarkers for exposure and susceptibility to carcinogenesis.