Award
NIH Reporter #5R01AI045818-26
RNA-dependent RNA Polymerase
Recipient
University of North Carolina at Chapel Hill, Department of Microbiology/Immunology/ViroLOGY
Award Amount
$404,270.00
Ceiling
$404,270.00
Awarded
August 20, 2025
Identifier
5R01AI045818-26
This NIH grant funds research on RNA-dependent RNA polymerase to understand RNA virus mechanisms and develop treatments and vaccines for RNA viral infections such as Ebola and SARS coronavirus.
Description
RNA viruses represent an existing and emerging threat to US public health. The proposed studies will create important knowledge that should contribute to development of strategies to treat and to prevent RNA viral infections, including those of current concern: Ebola virus, enterovirus D68, and Severe acute respiratory syndrome coronavirus. Achievement of the goals of the application will provide novel targets and mechanisms for development of vaccines and inhibitors to prevent and to treat infections by RNA viruses.