Award
National Institute of Mental Health 1R21MH140335-01A1
Elucidating the Role of the Hippocampus in Motor Memory using Temporal Interference Stimulation
Recipient
Utah State Higher Education System--University of Utah
Award Amount
$402,802.00
Ceiling
$402,802.00
Awarded
March 10, 2026
Identifier
1R21MH140335-01A1
This award funds research to investigate how temporal interference stimulation affects hippocampal activity and motor memory in healthy adults, using functional MRI to provide causal evidence of hippocampal involvement in motor learning.
Description
The project aims to causally test the role of the hippocampus in motor memory in young healthy adults using a novel non-invasive intervention called temporal interference stimulation (TIS). The study will evaluate the effect of TIS on hippocampal responses related to motor learning using functional magnetic resonance imaging (MRI). The hypothesis is that HC-TIS will enhance offline motor learning by modulating hippocampal responses, providing causal evidence for the hippocampus's role in motor learning and validating TIS as a technique for deep brain stimulation.