Award
National Institute of Diabetes and Digestive and Kidney Diseases 5R01DK110162-08
Molecular and Cellular Mechanisms of the Lysosomal Storage Disease Cystinosis
Recipient
SCRIPPS RESEARCH INSTITUTE, THE
Award Amount
$740,732.00
Ceiling
$740,732.00
Awarded
June 25, 2025
Identifier
5R01DK110162-08
This award supports research on cystinosis, a lysosomal storage disorder, aiming to understand CMA regulation and develop novel therapies to improve kidney function.
Description
Research project focused on elucidating the molecular mechanisms regulating chaperone-mediated autophagy (CMA) activity in cystinosis and developing small-molecule activators of CMA to improve cellular and renal function.