Award
NIH Reporter #3UC2AR082195-02S2
Comprehensive functional phenotyping of trigeminal neurons innervating temporomandibular joint (TMJ) tissues in male, female and aged mice, primates, and humans with and without TMJ disorders (TMJD)
Recipient
University of Texas Health Science Center, San Antonio, TX
Award Amount
$447,319.00
Ceiling
$447,319.00
Awarded
August 28, 2026
Identifier
3UC2AR082195-02S2
This project focuses on improving sample processing and analytical methods to study trigeminal neurons in TMJ tissues across various species, aiming to understand TMJ disorders and develop effective therapies.
Description
The project aims to enhance the processing of human samples and implement advanced analytical methodologies to study trigeminal neurons related to TMJ disorders. It focuses on expanding sample processing, especially from small tissue samples, and employing sophisticated computational analysis techniques to better understand the molecular mechanisms underlying TMJ pain and heterogeneity.