Award
NIH Reporter #1F31CA305882-01A1
Determining the Role of TOX in the Maintenance of CD8+ T cell Exhaustion and Memory Development
Recipient
Not specified
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
June 23, 2026
Identifier
1F31CA305882-01A1
Research project awarded by the National Cancer Institute to study the role of TOX in CD8+ T cell exhaustion and memory development, with implications for cancer immunotherapy.
Description
The project focuses on the role of the transcription factor TOX in T cell exhaustion and memory formation. The project involves generating conditional knockout mice and conducting adoptive transfer experiments. It aims to inform potential cancer immunotherapy strategies targeting TOX.