# NIH Reporter #1R01AI201678-01

Mycoplasma genitalium in Women: Natural History, Clinical Sequelae, and Host-Microbiome-Mediated Clearance

**Recipient:** University of Maryland Baltimore

**Award Amount:** $804,984.00
**Ceiling:** $804,984.00

**Awarded:** September 17, 2026

**Identifier:** 1R01AI201678-01

A research project funded by the National Institute of Allergy and Infectious Diseases to study the natural history, clinical effects, and microbiome interactions of Mycoplasma genitalium in women, focusing on infection epidemiology, disease associations, and spontaneous clearance mechanisms.

### Description

This project studies Mycoplasma genitalium (MG), an emerging drug-resistant sexually transmitted infection affecting women's health. It aims to define the epidemiology, clinical sequelae, and microbiome factors influencing MG infection and clearance, leveraging the NIH Longitudinal Study of Vaginal Flora cohort. The study addresses gaps in understanding MG's natural history, its association with syndromes like cervicitis and pelvic inflammatory disease, and antibiotic resistance challenges.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11431070)