Award
National Institute of Neurological Disorders and Stroke 11405390
Intermediate-sized Expanded Access Protocol for CNM-Au8 in Amyotrophic Lateral Sclerosis (ALS)
Recipient
New York University School of Medicine
Awarded
September 11, 2025
Identifier
11405390
Award for an expanded access protocol for CNM-Au8 in ALS patients to evaluate safety and biomarkers, funded by NIH.
Description
The project involves an expanded access program for CNM-Au8 in ALS patients across the United States. The study aims to evaluate safety, survival, and disease progression biomarkers. The project is funded by NIH (National Institute of Neurological Disorders and Stroke) under grant PA-24-254. The project will use up to 10 ALS trial centers and virtual enrollment via Synapticure. Biomarkers such as Neurofilament Light Chain, UCHL1, and serum creatinine will be analyzed.