Award
NIH Reporter #5R01DE031476-05
Personalized Strategies for Periodontal Tissue Regeneration - A Converged Biofabrication Approach
Recipient
University of Michigan at Ann Arbor, MI, United States
Award Amount
$534,474.00
Ceiling
$534,474.00
Awarded
April 29, 2026
Identifier
5R01DE031476-05
Development of personalized biofabricated scaffolds for periodontal tissue regeneration to prevent tooth loss due to gum disease.
Description
This project aims to develop personalized, tissue-specific scaffolds using biofabrication techniques such as Melt ElectroWriting (MEW) and ceramic printing to support bone and periodontal ligament (PDL) regeneration. The project will optimize scaffolds for defects with moderate and minimal surrounding bone, using clinically relevant animal models to expedite translation. The project focuses on developing personalized scaffolds for periodontal regeneration, aiming to translate biofabrication techniques into clinical therapies for periodontal tissue regeneration, potentially saving millions of teeth.