Award
NIH Reporter #1R01HL182878-01A1
Role of Tip60 Acetyltransferase in Cardiac Regeneration and Repair
Recipient
Medical College of Wisconsin, Milwaukee, WI, United States
Award Amount
$610,494.00
Ceiling
$610,494.00
Awarded
August 12, 2026
Identifier
1R01HL182878-01A1
Research project funded by NHLBI to study Tip60 acetyltransferase's role in cardiac regeneration and develop therapeutic inhibitors, potentially advancing heart attack recovery treatments.
Description
This project aims to define the role of Tip60 isoforms Tip60α and Tip60β in cardiac regeneration, develop small-molecule inhibitors targeting Tip60, and elucidate mechanisms to promote heart repair. The research could lead to novel therapies for heart attack recovery by modulating Tip60 activity to promote cardiac regeneration.