Award
NIH Reporter #1R15HL168608-01
Identifying interconnections of the disparities in childhood obesity
Recipient
Auburn University at Auburn
Award Amount
$441,498.00
Ceiling
$441,498.00
Awarded
May 03, 2023
Identifier
1R15HL168608-01
A research project funded by the National Heart Lung and Blood Institute to study the associations among childhood obesity, oxidative stress, inflammation, and urinary volatile organic compounds, aiming to identify noninvasive biomarkers for early detection of obesity-related metabolic dysfunction.
Description
This study evaluates urinary oxidative stress, inflammatory markers, and volatile organic compounds as potential noninvasive biomarkers of obesity-related metabolic changes in children, and investigates whether oxidative stress directly contributes to VOC production. The research aims to determine associations among childhood obesity, urinary biomarkers, and VOC metabolites, and to establish if oxidative stress induces VOC release. The findings may identify noninvasive metabolic biomarkers and provide insights into the biological relationships among obesity, oxidative stress, and urinary VOCs.