Award
National Heart, Lung, and Blood Institute 1F32HL182304-01
Defining the function of C/EBP-beta and its downstream target PSMB9 in atherosclerosis
Recipient
Emory University, Atlanta, GA, United States
Award Amount
$81,040.00
Ceiling
$81,040.00
Awarded
September 12, 2025
Identifier
1F32HL182304-01
This award funds research to understand the role of C/EBP-beta and PSMB9 proteins in atherosclerosis development, focusing on endothelial cell dysfunction and inflammation, with the goal of identifying new therapeutic targets for cardiovascular disease.
Description
The project aims to define how two proteins important for inflammation, CCAAT/Enhancer Binding Protein Beta and Proteasome Subunit Beta 9 (PSMB9), are involved in disturbed blood flow leading to endothelial dysfunction, inflammation, and atherosclerosis. The research involves in vitro and in vivo studies to identify therapeutic targets for cardiovascular disease.