Award
National Heart, Lung, and Blood Institute 5K23HL171862-02
Myeloid-derived suppressor cells modulate disease severity in children with viral lower respiratory tract infections
Recipient
RESEARCH INST NATIONWIDE CHILDREN'S HOSP
Award Amount
$180,199.00
Ceiling
$180,199.00
Awarded
August 27, 2025
Identifier
5K23HL171862-02
Research grant investigating the role of MDSC in pediatric viral LRTI to identify therapeutic targets and improve clinical outcomes.
Description
This research grant supports a project studying the role of myeloid-derived suppressor cells (MDSC) in children with viral lower respiratory tract infections (LRTI). The project aims to identify MDSC as contributors to the immune response, understand their impact on disease severity, and explore therapeutic targets including PD-1 pathway inhibition. The award supports career development of a clinician-scientist.