Award
NIH Reporter #2R01HL148123-05A1
The Role of TGF-beta Activation and Signaling in Aortic Stenosis Progression
Recipient
Oklahoma Medical Research Foundation
Award Amount
$786,750.00
Ceiling
$786,750.00
Awarded
August 21, 2026
Identifier
2R01HL148123-05A1
NIH-funded research project investigating how anemia and oscillatory shear stress activate TGF-beta signaling in aortic stenosis progression, aiming to identify treatment targets and biomarkers for heart failure and fibrotic diseases.
Description
Research project funded by NIH focusing on molecular mechanisms of aortic stenosis and potential therapeutic interventions. The project involves advanced biochemical and transcriptomic techniques and aims to identify biomarkers and treatment targets for fibrotic cardiovascular diseases.