Award
National Institute on Drug Abuse 1R03DA055970-01A1
L-type Calcium Channel SNP rs1006737: characterizing the genetic risks in MUD (Methamphetamine Use Disorder)
Recipient
University of Hawaii at Manoa, Honolulu, HI, United States
Award Amount
$218,250.00
Ceiling
$218,250.00
Awarded
September 21, 2023
Identifier
1R03DA055970-01A1
This NIH-funded research project aims to understand the genetic risks associated with methamphetamine use disorder by studying the L-type calcium channel SNP rs1006737 and its impact on inflammation and cognition.
Description
Research project studying individuals with methamphetamine use disorder (MUD) to determine whether the genetic variant rs1006737 A allele is associated with craving, depressive symptoms, cognitive deficits, disrupted sleep patterns, and reduced heart rate variability. The study investigates brain inflammation and genetic factors, particularly variants of the L-type calcium channel gene, in response to METH exposure and withdrawal using neuroimaging methodologies.