Award
NIH Reporter #1R21AI202888-01
Clinical Trajectory-Based Modeling of C. difficile to Link Individual Risk Profiles to Healthcare Burden
Recipient
University of California, San Francisco
Award Amount
$246,000.00
Ceiling
$246,000.00
Awarded
August 17, 2026
Identifier
1R21AI202888-01
The award funds research to create and validate models of CDI progression using health records to improve infection control and antibiotic use, aiming to reduce healthcare burden.
Description
This project aims to develop and validate new mathematical models representing the full clinical trajectory of Clostridioides difficile infection (CDI), from colonization to infection to relapse, using electronic health record data. The work will identify stage-specific risk factors, evaluate intervention strategies, and project population-level impacts to improve infection control and antibiotic stewardship.