Award
National Institute of Neurological Disorders and Stroke 5R03NS136069-02
Exploring the Pathophysiology of CMT1G
Recipient
Albany Medical College, Albany, NY, United States
Award Amount
$81,750.00
Ceiling
$81,750.00
Awarded
March 05, 2025
Identifier
5R03NS136069-02
The award supports research to develop a knock-in mouse model to study the PMP2 p.Ile50del mutation's role in Charcot-Marie-Tooth disease type 1G, aiming to understand molecular dysregulation and identify therapeutic targets.
Description
This project focuses on modeling Charcot-Marie-Tooth disease type 1G caused by mutations in the PMP2 gene, using advanced genetic and molecular biology techniques to understand disease mechanisms and potential therapeutic targets.