Award

National Institute of General Medical Sciences 5R01GM035215-36

Molecular Mechanisms of Membrane Transport

Recipient

University of Virginia, Charlottesville, VA

Award Amount

$349,314.00

Ceiling

$349,314.00

Awarded

April 17, 2026

Identifier

5R01GM035215-36

This award supports research on the molecular mechanisms of nutrient transport in Escherichia coli, focusing on TonB-dependent outer-membrane proteins critical for bacterial physiology and antibiotic targeting.

Description

The project focuses on bacterial membrane transport mechanisms, especially TonB-dependent transporters. It aims to understand structural states in vivo and the role of lipopolysaccharides. Uses advanced spectroscopic techniques in intact bacteria.

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