Award
National Institute of General Medical Sciences 5R35GM134886-07
Illuminating the gene regulatory strategies underlying yeast meiosis and beyond
Recipient
University of California Berkeley
Award Amount
$467,635.00
Ceiling
$467,635.00
Awarded
January 23, 2026
Identifier
5R35GM134886-07
Research project funded by NIGMS to study gene regulation in yeast meiosis, focusing on LUTIs, non-AUG translation, and protein complex formation, using genomic and machine learning methods to advance understanding of gene expression and fertility.
Description
This project aims to investigate gene regulation during meiosis using budding yeast as a model. The research focuses on understanding the regulation of LUTIs (long undecoded transcript isoforms), the translation of non-AUG start codons, and the formation of protein complexes within cells. The study leverages machine learning, genomic approaches, and yeast genetics to uncover fundamental principles of gene expression regulation relevant to human fertility and health.